Acoustic Radiation Force Impulse Elastography: A Non-Invasive Alternative to Liver Biopsy
نویسندگان
چکیده
The prognosis of chronic liver disease depends on the progression of liver fibrosis. Liver biopsy is recommended as the gold standard method for determining fibrosis stage, prognosis and therapeutic indications in patients with chronic liver disease. However, liver biopsy is an invasive procedure associated with a risk of potentially serious complications. Approximately 1–3% of patients require hospitalization for complications, and a quarter of them report pain after percutaneous liver biopsy. The diagnostic accuracy of liver biopsy for assessing liver fibrosis is influenced by the quality of the biopsy samples. In addition, there are several absolute or relative contraindications to liver biopsy, including severe coagulopathy. A safe and non-invasive alternative to liver biopsy is therefore needed for assessing liver fibrosis in daily clinical practice.
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